抗切除修复交叉互补基因1抗体产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）
抗切除修复交叉互补基因1抗体产品说明
ERCC1蛋白是动物内重要的DNA修复基因家族成员之一。在人体内它的低表达往往伴随着基因不稳定性增加,从而产生肿瘤恶性变的发生。
The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand.
mol wt:36kDa
Other Aliases:
Excision Repair Cross Complementing 1; DNA excision repair protein ERCC-1; COFS4; UV20; DNA excision repair protein ERCC1; ERCC 1; Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1; Excision repair protein; UV 20; UV20xy-9662R EFR3AEFR3A蛋白抗体
xy-9660R ENAHENAH蛋白抗体
xy-7610R ETHE1乙基丙二酸脑病蛋白抗体
xy-1722R E2F3转录因子E2F-3抗体
xy-1734R E2F5转录因子E2F-5抗体
xy-1726R ERCC1DNA切除修复蛋白1抗体
xy-1750R E2F6转录因子E2F6抗体
xy-1751R EAAT2胶质细胞谷氨酸运载蛋白2抗体
xy-1752R EAAT3胶质细胞谷氨酸运载蛋白3抗体(神经/上皮细胞谷氨酸运载蛋白)
xy-1753R ECE2内皮素转化酶2抗体
xy-1754R ECP嗜酸性粒细胞阳离子蛋白抗体
xy-1755R EGFL7类表皮生长因子域7抗体
xy-1756R alpha Elastinα弹性蛋白抗体
xy-2041R Yellow fever virus envelope glycoprotein E黄热病毒包膜糖蛋白抗体
xy-1831R ErbB 2HER2受体抗体
xy-1399R E2F4转录因子E2F-4抗体
xy-3104R Phospho-EGFR (Ser991)磷酸化表皮生长因子受体抗体
xy-3111R Phospho-EGFR(Tyr845)磷酸化表皮生长因子受体抗体
xy-3112R Phospho-EGFR (Tyr998)磷酸化表皮生长因子受体抗体
xy-3133R Phospho-Ezrin (Tyr353)磷酸化埃兹蛋白抗体
xy-3134R Phospho-Ezrin (Thr567)磷酸化埃兹蛋白抗体
xy-3175R Phospho-ELk1 (Ser383)磷酸化细胞转录因子ELK1抗体
xy-3126R Phospho-EphA2 (Tyr594)磷酸化酪氨酸蛋白激酶A2受体抗体
xy-2764R Ephrin BEphrin B抗体
xy-3217R phospho-Ephrin B (Tyr329)磷酸化Ephrin B抗体
xy-3167R phospho-Ephrin B (Tyr316)磷酸化Ephrin B抗体
抗切除修复交叉互补基因1抗体
