PerCP anti-human CD11a
- 品牌:Biolegend
- 型号:350608
- 产地:美国
- 供应商:上海恒斐生物科技有限公司
- 供应商报价:¥2925
- 标签:PerCP anti-human CD11a、PerCP anti-human CD11a价格、PerCP anti-human CD11a厂家、、、上海恒斐生物科技有限公司
| Clone | TS2/4 |
| Isotype | Mouse IgG1, κ |
| Reactivity | Human |
| Immunogen | HLA-DR CTL line |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). |
| Preparation | The antibody was purified by affinity chromatography and conjugated with PerCP under optimal conditions. The solution is free of unconjugated PerCP and unconjugated antibody. |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 µl per million cells or 5 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Applications | FC - Quality tested |
| Application Notes | Additional reported applications (for relevant formats) include: immunoprecipitation1, 2. Note: the antibody TS2/4 recognizes the β-propeller domain of CD11a and only immunoprecipitates the CD11a/CD18 complex. |
| Application References | 1. Huang C and Springer TA. 1997. P. Natl. Acad. Sci. USA 94:3162. (IP) |
| Description | CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). |
| Storage | The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |