本公司提供科研
LSAMP大脑边缘系统相关膜蛋白抗体，抗体质量可靠，订购
LSAMP大脑边缘系统相关膜蛋白抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：
大脑边缘系统相关膜蛋白抗体英文名称：
Anti-LSAMP货号：bs-11091R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 37kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：LSAMP is a neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system expressed on the surface of somata and proximal dendrites of neurons. It is a member of the immunoglobulin (Ig) superfamily and belongs to the IgLON subfamily of cell adhesion molecules. LSAMP contains three Ig domains and a glycosylphosphatidylinositol anchor. It is a highly conserved protein between rodents and humans (99% sequence identity) and it is involved in the regulation of neurite outgrowth and mediation of proper circuit formation of limbic pathways. This suggests that LSAMP plays an important role in the development and function of the limbic system. In addition, LSAMP may function as a tumor suppressor in renal carcinomas.Function : Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection.Subcellular Location : Cell membrane.Tissue Specificity : Expressed on limbic neurons and fiber tracts as well as in single layers of the superior colliculus, spinal chord and cerebellum.Similarity : Belongs to the immunoglobulin superfamily. IgLON family.Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
