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Anti-Myelin Protein Zero外周髓磷脂P0蛋白/P0蛋白抗体

产品信息
  • 本公司提供科研Myelin Protein Zero外周髓磷脂P0蛋白/P0蛋白抗体,抗体质量可靠,订购Myelin Protein Zero外周髓磷脂P0蛋白/P0蛋白抗体请联系在线客服或者销售人员。
    抗体参数如下>>>>
    中文名称:外周髓磷脂P0蛋白/P0蛋白抗体
    英文名称:Anti-Myelin Protein Zero
    货号:bs-0337R
    抗体来源:兔
    克隆类型:多克隆
    蛋白分子量:predicted molecular weight: 24kDa
    纯化方法:affinity purified by Protein A
    交叉反应:hu, rat, mo, hrs, dog, pig, bov, Gpig, Rb
    测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
    (石蜡切片需做抗原修复)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    产品背景介绍:Myelin protein-zero is the major structural protein of peripheral myelin, accounting for more than 50% of the protein present in the sheath of peripheral nerves. Expression of the gene encoding Myelin protein-zero (MPZ) is restricted to Schwann cells; MPZ is not found in the CNS. An integral membrane glycoprotein of ~28kDa, Myelin protein-zero is thought to link adjacent lamellae and thereby stabilize the myelin assembly. The other 3 major components of myelin are myelin basic protein, myelin proteolipid protein and myelin-associated glycoprotein.Subunit : Homodimer and homotetramer.Subcellular Location : Cell membrane; Single-pass type I membrane protein.Tissue Specificity : Found only in peripheral nervous system Schwann cells.Similarity : Belongs to the myelin P0 protein family.Contains 1 Ig-like V-type (immunoglobulin-like) domain.成熟的周围神经系统髓鞘主要的蛋白为P0蛋白,分子量28KDa,它具有单个跨膜区,是IgG超家族的成员之一。产品图片Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Myelin Protein Zero Polyclonal Antibody, Unconjugated(bs-0337R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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