本公司提供科研NRIP雄激素受体复合物相关蛋白抗体（核受体相互作用蛋白），抗体质量可靠，订购NRIP雄激素受体复合物相关蛋白抗体（核受体相互作用蛋白）请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称：雄激素受体复合物相关蛋白抗体（核受体相互作用蛋白） 英文名称：Anti-NRIP 货号：bs-6210R 抗体来源：兔 克隆类型：多克隆 蛋白分子量：predicted molecular weight: 94kDa 纯化方法：affinity purified by Protein A 交叉反应：hu, mo, rat 测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍：WD-repeat proteins are a large family of eukaryotic proteins coordinating multi-protein complex assemblies. Their role has been implicated in multiple cellular processes including signal transduction, transcriptional regulation, cell cycle control and apoptosis. NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up-regulates their transcriptional activity, thereby functioning as a nuclear receptor co-activator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer, thus indicating a potential therapeutic intervention. Northern Blot analysis detects a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
