Anti-PCSK9/NARC1神经细胞凋亡调节转化蛋白1抗体（前蛋白转化酶枯草溶菌素9）

本公司提供科研PCSK9/NARC1神经细胞凋亡调节转化蛋白1抗体（前蛋白转化酶枯草溶菌素9），抗体质量可靠，订购PCSK9/NARC1神经细胞凋亡调节转化蛋白1抗体（前蛋白转化酶枯草溶菌素9）请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：神经细胞凋亡调节转化蛋白1抗体（前蛋白转化酶枯草溶菌素9）
英文名称：Anti-PCSK9/NARC1
货号：bs-6060R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 59/73kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：May be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis.Function : The precursor protein but not the mature protein may form multimers.Subunit : The precursor protein but not the mature protein may form multimers.Subcellular Location : Secreted.Tissue Specificity : Expressed in neuro-epithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells.Post-translational modifications : The soluble zymogen undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage of its propeptide that remains associated with the secreted enzyme.Similarity : Belongs to the peptidase S8 family. Contains 1 peptidase S8 domain.前蛋白转化酶枯草溶菌素9(PCSK9)是近年来新发现的一种与调节脂质代谢密切相关的基因,编码前蛋白转化酶NARC-1。Narc-1/pcsk9可通过调节细胞表面的低密度脂蛋白受体(LDLR)水平,参与脂质代谢,从而在动脉粥样硬化性疾病的发生、发展中发挥重要作用。