本公司提供科研phospho-PAK6(Ser165)磷酸化P21蛋白激活的蛋白激酶6，抗体质量可靠，订购phospho-PAK6(Ser165)磷酸化P21蛋白激活的蛋白激酶6请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称：磷酸化P21蛋白激活的蛋白激酶6 英文名称：Anti-phospho-PAK6(Ser165) 货号：bs-5556R 抗体来源：兔 克隆类型：多克隆 蛋白分子量：predicted molecular weight: 75kDa 纯化方法：affinity purified by Protein A 交叉反应：hu, mo, rat 测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍：This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.
