本公司提供科研
phospho-CASC3(Tyr181)磷酸化肿瘤易感候选基因3抗体，抗体质量可靠，订购
phospho-CASC3(Tyr181)磷酸化肿瘤易感候选基因3抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：
磷酸化肿瘤易感候选基因3抗体英文名称：
Anti-phospho-CASC3(Tyr181)货号：bs-5283R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 76kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, Rb, hrs, cow, chk
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：The multiprotein exon junction complex (EJC) is deposited on mRNAs upstream of exon–exon junctions as a consequence of pre-mRNA splicing. In mammalian cells, this complex serves as a key modulator of spliced mRNA metabolism. MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer. The function of MLN51 in mammals remains elusive. Its fly homolog, named barentsz, as well as the proteins mago nashi and tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte. Magoh and Y14, the human homologs of mago nashi and tsunagi, are core components of the exon junction complex (EJC). The EJC is assembled on spliced mRNAs and plays important roles in post-splicing events including mRNA export, nonsense-mediated mRNA decay, and translation. Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes.
