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phospho-CREB-1(Ser142)磷酸化CREB-1抗体，抗体质量可靠，订购
phospho-CREB-1(Ser142)磷酸化CREB-1抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：
磷酸化CREB-1抗体英文名称：
Anti-phospho-CREB-1(Ser142)货号：bs-5269R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 43kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, shp, cow, chk, hrs
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：The ATF/CREB family consists of transcription factors that function through binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2, ATF-1,ATF-2,ATF-3and ATF-4. these transcription factors share highly-related COOH terminal leucine zipper demerization and basic DNA bindings but are highly divergent in their amino terminal domains. Although each of the ATF/CREB proteins bind CREs in their homodimeric form, in cerain instances they also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. It has recentlybeen shown that protein kinase A-mediated CREB phosphorylation results in its binding to a 265kDa nuclear protein designated CBP (CREB-binding protein), which may reprecent a CREB co-activator.Subcellular Location : Nucleus.Similarity : Belongs to the bZIP family.Contains 1 bZIP domain.Contains 1 KID (kinase-inducible) domain.
