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Anti-Thioredoxin 2线粒体硫氧还蛋白2抗体

产品信息
  • 本公司提供科研Thioredoxin 2线粒体硫氧还蛋白2抗体,抗体质量可靠,订购Thioredoxin 2线粒体硫氧还蛋白2抗体请联系在线客服或者销售人员。
    抗体参数如下>>>>
    中文名称:线粒体硫氧还蛋白2抗体
    英文名称:Anti-Thioredoxin 2
    货号:bs-4256R
    抗体来源:兔
    克隆类型:多克隆
    蛋白分子量:predicted molecular weight: 12kDa
    纯化方法:affinity purified by Protein A
    交叉反应:hu, mo, rat, dog, pig, cow, Rb
    测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
    (石蜡切片需做抗原修复)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    产品背景介绍:Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.Subunit : Monomer.Subcellular Location : Mitochondrion.Tissue Specificity : Widely expressed in adult (at protein level) and fetal tissues.Similarity : Belongs to the thioredoxin family.Contains 1 thioredoxin domain.
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