本公司提供科研TP/thymidine phosphorylase胸苷磷酸化酶抗体，抗体质量可靠，订购TP/thymidine phosphorylase胸苷磷酸化酶抗体请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称：胸苷磷酸化酶抗体 英文名称：Anti-TP/thymidine phosphorylase 货号：bs-3809R 抗体来源：兔 克隆类型：多克隆 蛋白分子量：predicted molecular weight: 50kDa 纯化方法：affinity purified by Protein A 交叉反应：hu 测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍：In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.Subunit : Homodimer.Similarity : Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.胸苷磷酸化酶（TP）是一种分子量为50-55kDa的蛋白，在氟嘧啶转化过程中起重要作用。TP具有血管生成活性，与血小板源性内皮细胞生长因子的结构和作用相似，因此又被称为肿瘤相关血管生长因子。其可能通过血管生成作用促进癌细胞的生长和转移。
