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Calbindin/Calbindin D28k钙结合蛋白D28K抗体,抗体质量可靠,订购
Calbindin/Calbindin D28k钙结合蛋白D28K抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
钙结合蛋白D28K抗体英文名称:
Anti-Calbindin/Calbindin D28k货号:bs-3758R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 29kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, hrs, dog, pig, cow, Rb
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:Calbindin D28k is a member of a large family of intracellular calcium binding proteins, containing EF hand calcium binding motifs, and related to calmodulin and troponin C. The biological roles of Calbindin D28k include calcium regulation and calcium dependent signalling in neurons and during development. Decreases in Calbindin D28k abundance, or loss of Calbindin D28k immunoreactivity, is found in models of neurological disorders such as epilepsy, and in neurodegenerative diseases. Calbindin antibody is often used as a marker for cerebellum Purkinje cells.Function : Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.Subunit : Interacts with RANBP9.Similarity : Belongs to the calbindin family.Contains 5 EF-hand domains.