Anti-RSK3/Ribosomal S6 kinase 3核糖体蛋白S6激酶家族RSK3抗体

本公司提供科研RSK3/Ribosomal S6 kinase 3核糖体蛋白S6激酶家族RSK3抗体，抗体质量可靠，订购RSK3/Ribosomal S6 kinase 3核糖体蛋白S6激酶家族RSK3抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：核糖体蛋白S6激酶家族RSK3抗体
英文名称：Anti-RSK3/Ribosomal S6 kinase 3
货号：bs-3553R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 90kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：RSK3(Ribosomal S6 kinase 3)is a member of a family of 90-kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases that are activated in response to mitogenic stimuli, including extracellular signal-regulated protein kinases Erk1 and Erk2. Rsk3 is a distinct isoform of p90Rsk that translocates to the cell nucleus, phosphorylates potential nuclear targets and may have a unique upstream activator. Several sites, such as Ser380, Thr359, Ser363 and Thr573, are important for its activation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.