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Anti-Phospho-PDGF Receptor beta (Tyr1009)磷酸化血小板源性生长因子受体-B抗体

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  • 本公司提供科研Phospho-PDGF Receptor beta (Tyr1009)磷酸化血小板源性生长因子受体-B抗体,抗体质量可靠,订购Phospho-PDGF Receptor beta (Tyr1009)磷酸化血小板源性生长因子受体-B抗体请联系在线客服或者销售人员。
    抗体参数如下>>>>
    中文名称:磷酸化血小板源性生长因子受体-B抗体
    英文名称:Anti-Phospho-PDGF Receptor beta (Tyr1009)
    货号:bs-3321R
    抗体来源:兔
    克隆类型:多克隆
    蛋白分子量:predicted molecular weight: 190kDa
    纯化方法:affinity purified by Protein A
    交叉反应:hu, mo, rat
    测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
    (石蜡切片需做抗原修复)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    产品背景介绍:The PDGF Receptor Type A (Alpha platelet-derived growth factor receptor precursor, CD140a antigen), a 170kD protein, binds all three isoforms of PDGF with high affinity whereas the PDGF Receptor Type B, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity. Both receptors are transmembranous, ligand activated protein tyrosine kinases, which phosphorylate a number of important signal transduction proteins, which are bound with differential affinities via SH2 domains. The response of any given cell to PDGF will depend on the types of receptors displayed on the surface and isoforms of PDGF present in the extracellular environment.细胞膜受体(Membrane Receptors)
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