Anti-Endothelial lipase内皮脂肪酶抗体

本公司提供科研Endothelial lipase内皮脂肪酶抗体，抗体质量可靠，订购Endothelial lipase内皮脂肪酶抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：内皮脂肪酶抗体
英文名称：Anti-Endothelial lipase
货号：bs-2397R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 53kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, hrs, pig, dog, chk
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. [provided by RefSeq, Jul 2008].Function : Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin.Subunit : Head to tail homodimer.Subcellular Location : Secreted.Tissue Specificity : High level of expression in the liver, placenta, lung, thyroid, kidney, testis and in the corpus luteum of the ovary. Expressed also in coronary artery endothelial cells, umbilical vein endothelial cells and in hepatocytes and osteosarcoma cell lines. Not detected in heart, brain and muscle.Similarity : Belongs to the AB hydrolase superfamily. Lipase family.Contains 1 PLAT domain.EL被确定为甘油三酯脂肪酶家族的新成员，由于EL是由血管内皮细胞合成和分泌，因此被命名为内皮脂肪酶，相应的基因命名为内皮脂肪酶基因(endothelial lipase gene，LIPG)。EL也是一种分泌型蛋白，由483个氨基酸组成，分子量约55kD，在人体多种组织中都有表达：冠状动脉、胎盘、甲状腺、肝脏、肺脏、肾脏、睾丸和卵巢等组织中都可发现。