本公司提供科研LAMA3/Laminin 5 alpha 3层粘蛋白α3抗体，抗体质量可靠，订购LAMA3/Laminin 5 alpha 3层粘蛋白α3抗体请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称：层粘蛋白α3抗体 英文名称：Anti-LAMA3/Laminin 5 alpha 3 货号：bs-1969R 抗体来源：兔 克隆类型：多克隆 蛋白分子量：predicted molecular weight: 190(human, rat)367(mo)kDa 纯化方法：affinity purified by Protein A 交叉反应：hu, mo, rat 测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍：Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin 5 is an isoform composed of three distinct subunits, alpha 3, beta 3 and gamma 2, which are bound to each other in a cross-shaped molecule by disulphide bonds. It is a complex glycoprotein thought to be involved in cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes. It is also involved in signal transduction via tyrosine phosphorylation of pp125-FAK and p80, and differentiation of keratinocytes. The laminin alpha 3 subunit is also thought to be a component of laminin 6 and laminin 7.
