Anti-NGB/neuroglobin脑红蛋白/神经血红蛋白/神经球蛋白抗体

本公司提供科研NGB/neuroglobin脑红蛋白/神经血红蛋白/神经球蛋白抗体，抗体质量可靠，订购NGB/neuroglobin脑红蛋白/神经血红蛋白/神经球蛋白抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：脑红蛋白/神经血红蛋白/神经球蛋白抗体
英文名称：Anti-NGB/neuroglobin
货号：bs-1859R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 17kDa
纯化方法：affinity purified by Protein A
交叉反应：mo, rat, hu, Rb, cow, pig
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Neuroglobin, a 151 amino acid reside protein, mainly expressed in vertebrate brain and retina, is a recently identified member of the globin superfamily. Augmenting O2 supply, neuroglobin promotes survival of neurons upon hypoxic injury, potentially limiting brain damage. Moreover, neuroglobin may be a novel oxidative stress-responsive sensor for signal transduction in the brain. Neuroglobin expression is increased by neuronal hypoxia in vitro and focal cerebral ischemia in vivo, and neuronal survival after hypoxia is reduced by inhibiting neuroglobin expression with an antisense oligodeoxynucleotide and enhanced by neuroglobin overexpression.Subunit : Monomer. Homodimer and homotetramer; disulfide-linked (By similarity).Subcellular Location : Perikaryon (By similarity).Tissue Specificity : Predominantly expressed in brain, the strongest expression is seen in the frontal lobe, the subthalamic nucleus and the thalamus.Similarity : Belongs to the globin family.Neuroglobin是一种在神经组织和神经冲动中携氧、转运氧气和供氧的特异性蛋白,并和神经组织微循环有关,神经球蛋白能在缺氧的环境下保护神经元.