本公司提供科研
KCNA5钾电压阀门通道混合器相关亚家族成员5抗体,抗体质量可靠,订购
KCNA5钾电压阀门通道混合器相关亚家族成员5抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
钾电压阀门通道混合器相关亚家族成员5抗体英文名称:
Anti-KCNA5货号:bs-1837R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 67kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, pig, dog, cow, Rb, chk
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12.Subunit : Heterotetramer of potassium channel proteins. Interacts with DLG1, which enhances channel currents. Forms a ternary complex with DLG1 and CAV3 (By similarity). Interacts with UBE2I.Subcellular Location : Membrane; Multi-pass membrane protein.Tissue Specificity : Pancreatic islets and insulinoma.Similarity : Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.产品图片Antigen: bs-1837P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000; TMB(C-0024) staining; Read the data in MicroplateReader by 450nm.