本公司提供科研Contactin 6/NB3/CNTN6神经细胞NB3特定蛋白抗体，抗体质量可靠，订购Contactin 6/NB3/CNTN6神经细胞NB3特定蛋白抗体请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称：神经细胞NB3特定蛋白抗体 英文名称：Anti-Contactin 6/NB3/CNTN6 货号：bs-1797R 抗体来源：兔 克隆类型：多克隆 蛋白分子量：predicted molecular weight: 113kDa 纯化方法：affinity purified by Protein A 交叉反应：hu, mo, rat 测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍：Contactin 6 is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein which functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system.Function : Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination.Subunit : Belongs to the immunoglobulin superfamily. Contactin family.Contains 4 fibronectin type-III domains.Contains 6 Ig-like C2-type (immunoglobulin-like) domains.Subcellular Location : Cell membrane.Tissue Specificity : Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord.
