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Anti-CA II/Carbonic anhydrase 2碳酸酐酶2抗体

产品信息
  • 本公司提供科研CA II/Carbonic anhydrase 2碳酸酐酶2抗体,抗体质量可靠,订购CA II/Carbonic anhydrase 2碳酸酐酶2抗体请联系在线客服或者销售人员。
    抗体参数如下>>>>
    中文名称:碳酸酐酶2抗体
    英文名称:Anti-CA II/Carbonic anhydrase 2
    货号:bs-1709R
    抗体来源:兔
    克隆类型:多克隆
    蛋白分子量:predicted molecular weight: 29kDa
    纯化方法:affinity purified by Protein A
    交叉反应:hu, rat, mo
    测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
    (石蜡切片需做抗原修复)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    产品背景介绍:Carbonic anhydrase II (CAII) is a single polypeptide chain of molecular weight 29kDa. It is present in the cytosol of most tissues, but highest concentrations are found, like Carbonic Anhydrase I, in erythrocytes. The concentration in erythrocytes is about 20µM. It catalyses the hydration of CO2 and the hydrolysis of esters. Zn2+ ion cofactor is required for enzyme activity. Certain point mutations occur without apparent clinical effect, however, complete absence leads to mild mental retardation and cerebral calcification, osteoporosis and renal tubular acidosis. Also known as: Carbonic anhydrase Ⅱ; CA 2; CA II; CA2; CAII; Car 2; Car2; Carbonate dehydratase II; Carbonic anhydrase 2 ; Carbonic anhydrase B; Carbonic anhydrase C; Carbonic anhydrase II; Carbonic dehydratase.Subunit : Interacts with SLC4A4. Interaction with SLC4A7 regulates SLC4A7 transporter activity.Subcellular Location : Cytoplasm.Similarity : Belongs to the alpha-carbonic anhydrase family.CA2(Carbonic anhydrase1)也是红细胞的主要蛋白质成分之一,是一种重要的锌酶,对血液及组织起到维持酸碱平衡的作用,协助体内组织排除二氧化碳,碳酸酐酶Ⅱ参与呼吸、钙化、酸碱平衡、骨吸收和各种体液形成的生理过程.
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