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Anti-GPCR SALPR/GPCR135/Relaxin Receptor 3G蛋白偶联受体135/松弛素受体3抗体

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  • 本公司提供科研GPCR SALPR/GPCR135/Relaxin Receptor 3G蛋白偶联受体135/松弛素受体3抗体,抗体质量可靠,订购GPCR SALPR/GPCR135/Relaxin Receptor 3G蛋白偶联受体135/松弛素受体3抗体请联系在线客服或者销售人员。
    抗体参数如下>>>>
    中文名称:G蛋白偶联受体135/松弛素受体3抗体
    英文名称:Anti-GPCR SALPR/GPCR135/Relaxin Receptor 3
    货号:bs-11405R
    抗体来源:兔
    克隆类型:多克隆
    蛋白分子量:predicted molecular weight: 51kDa
    纯化方法:affinity purified by Protein A
    交叉反应:hu, mo, rat
    测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
    (石蜡切片需做抗原修复)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    产品背景介绍:Relaxin Receptor 3 is a G protein-coupled receptor that binds Relaxin 3 and influences differentiation and maintenance of the nervous system. Relaxin Receptor 3 shares sequence similarity with somatostatin receptors and angiotensin receptors. It mediates central processing of sensory signals in the rat and is thought to be a modulator of stress responses. Relaxin Receptor 3 is present in the brain, with highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, and low level expression in cerebellum. In peripheral tissues there are high levels in adrenal glands and low levels in pancreas, salivery gland, placenta, mammary gland and testis.Function : GPCR SALPR, also known as Relaxin 3 Receptor 1 (RXFP3), is a G-protein coupled receptor that is one of the physiological targets for relaxin 3, an insulin-like hormone. Activation of GPCR SALPR results in phosphorylation of ERK1/2. GPCR SALPR has been implicated in anxiety and obesity. A role for relaxin 3 and GPCR SALPR in reproductive function through the hypothalamic-pituitary-gonadal (HPG) axis has also been described. Subcellular Location : Cell Membrane
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