本公司提供科研CLSTN2老年痴呆相关类钙粘蛋白CS2抗体，抗体质量可靠，订购CLSTN2老年痴呆相关类钙粘蛋白CS2抗体请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称：老年痴呆相关类钙粘蛋白CS2抗体 英文名称：Anti-CLSTN2 货号：bs-11339R 抗体来源：兔 克隆类型：多克隆 蛋白分子量： 纯化方法：affinity purified by Protein A 交叉反应：hu, rat 测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍：Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.Function : CLSTN2 (Alcadein gamma/Calsyntenin 2) is a member of the novel calsyntenin family of proteins that have been found to be localized in the postsynaptic membrane of excitatory central nervous system (CNS) synapses. It may play a role in postsynaptic Ca2+ signaling. Calsyntenin 2 structure is very similar to calsyntenin 1 in it's extracellular parts, but varies considerably in it's cytoplasmic segment.Subcellular Location : Membrane; single-pass type I membrane protein
