重组人谷氧还蛋白5|Human GLRX5|Glutaredoxin 5 Human RecombinantProSpec（蛋白质专家）是以色列一家具有超过16年历史的，专业从事细菌来源重组蛋白生产的先进生物技术公司。ProSpec生产多种细胞因子、生长因子、趋化因子、激素、酶、病毒抗原和许多其他重组蛋白。在研究团队和科学家们的努力下，ProSpec已经拥有超过1700种可用于癌症、细胞凋亡、发育、内分泌学、免疫学、神经科学、蛋白酶及干细胞研究用重组蛋白、多肽和抗体。10多年蛋白纯化方面的经验使ProSpec公司生产成本低、产量高、效率高，其蛋白产品不仅纯度高、生物活性高，价格也非常具有优势。同时ProSpec针对客户的需要提供自定义重组蛋白生产服务。 ProSpec向客户提供蛋白质产品、服务和技术授权。因为创新的产品、的客户服务和对细节的注重，ProSpec在科学界建立了良好的信誉，具有广泛的客户群，包括世界各地的学术、政府研究机构，生物技术和制药企业以及医院和基准实验室。
产品详情：CATALOGUE NUMBER
ENZ-480
SYNONYMS
Glutaredoxin-related protein 5 mitochondrial, Monothiol glutaredoxin-5, GLRX5, C14orf87, glutaredoxin 5, GRX5, FLB4739, PR01238, PRO1238, MGC14129.
INTRODUCTION
GLRX5 is small redox enzyme of approximately 100 amino acids which uses glutathione as a cofactor. GLRX5 is a mitochondrial protein, which is evolutionarily conserved. GLRX5 is oxidized by substrates, and reduced non-enzymatically by glutathione. GLRX5 is involved in the biogenesis of iron-sulfur clusters that are required for normal iron homeostasis. GLRX5 is necessary for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1. Defects in the GLRX5 gene are a cause of anemia sideroblastic pyridoxine-refractory autosomal recessive (PRARSA).
DESCRIPTION
GLRX5 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 177 amino acids (1-157 a.a.) and having a molecular mass of 18.8 kDa. GRX5 is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques.
SOURCE
Escherichia Coli.
PHYSICAL APPEARANCE
Sterile filtered colorless solution.
FORMULATION
GLRX5 solution containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol and 0.1M NaCl.
STABILITY
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
PURITY
Greater than 85% as determined by SDS-PAGE.
AMINO ACID SEQUENCE
MGSSHHHHHH SSGLVPRGSH MSGSLGRAAA ALLRWGRGAG GGGLWGPGVR AAGSGAGGGG SAEQLDALVK KDKVVVFLKG TPEQPQCGFS NAVVQILRLH GVRDYAAYNV LDDPELRQGI KDYSNWPTIP QVYLNGEFVG GCDILLQMHQ NGDLVEELKK LGIHSALLDE KKDQDSK.
USAGE
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
重组人谷氧还蛋白5|Human GLRX5|Glutaredoxin 5 Human Recombinant
温馨提示：不可用于临床ZL。
