Normal cells in the human body experience a three-dimensional environment, completely surrounded by other cells, membranes, fibrous layers and adhesion proteins. Living tissues and cells reside in a complex 3-D microenvironment formed by other cells and extracellular matrix. VECELL® 3D Cell Culture Dish is designed to reflect normal cell morphology & behavior for more realistic cell biology and function, in vivo-like morphology, and better intercellular interactions.
| Fibril | 2 - 10 µm |
| Fibril Length | 50 - 200 µm |
| Membrane Thickness | 50 - 70 µm |
| Porosity | 80 - 90 % |
The Permeable membrane that resembles in vivo conditions allows free movement of medium, and can be applied for drug metabolism test.
Culturing cells on flat plastic dish results in artificial 2-dimensional sheets of cells due to the strong interactions between cells and plastic dish surfaces. The experiments in vitro on monolayer of cells on plastic substrates may not reflect faithfully important aspects of cell behavior in vivo. Cells on VECELL® that resembles in vivo conditions creates a cell culture model that more closely reflects normal cell morphology and behavior to meet researchers' 3D cell culture requirements in such fields as toxicology, drug development, cancer and stem cell research, development and morphogenesis and tissue and organ engineering.
Cell proliferation on VECELL® (right) shows natural 3D morphology. Cultured cells on normal plastic dish (left) spread on the surface due to the strong interaction between the solid surface and cells.
Adhered cells made a cell layer after 26 days culture.
The viability of L929 cells on polystyrene dish significantly decreased after 9 days, whereas the cells on VECELL® were viable even after 11 days.
Mouse ES Cells differentiated on gelatin coated dish, whereas undifferentiated cells were cultured on VECELL®
| Product name | Product number | PKG size |
|---|---|---|
| Preset VECELL-12 (12 mm, 24 well) | VECELL-12 | 1 plate |
| Preset VECELL-30 (30 mm, 6 well) | VECELL-30 | 1 plate |
