Abiraterone Acetate/醋酸阿比特龙 CYP17YZ剂
- 品牌：chembest
- 型号：C13245
- 供应商：上海佰世凯化学科技有限公司
- 供应商报价：￥0
- 标签：Abiraterone Acetate/醋酸阿比特龙 CYP17抑制剂、Abiraterone Acetate/醋酸阿比特龙 CYP17抑制剂价格、Abiraterone Acetate/醋酸阿比特龙 CYP17抑制剂厂家、Abiraterone Acetate、、上海佰世凯化学科技有限公司
产品库
Abiraterone Acetate/醋酸阿比特龙
Molecula Formula:C26H33NO2
Molecular Weight: 391.55
Appearance: Off-White Solid
Purity:99%
CAS[154229-18-2]
Biological Activity:
Abiraterone acetate has been seen to be a novel steroidal inhibitor of CYP17A1(C17,20 lyase), a cytoochrome p450 complex, a rate-limiting enzyme in androgen biosynthesis resulting in inhibtion of testosterone production in both the adrenals and the testes.
References:
[1]. Vogiatzi, Paraskevi et al. Efficacy of abiraterone acetate in post-docetaxel castration-resistant prostate cancer. Expert Review of Anticancer Therapy (2010), 10(7), 1027-1030.
[2]. Reid, H. M. et al. Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate. Journal of Clinical Oncology (2010), 28(9), 1489-1495.
