| 产品名称： | Thyroid Hormone Receptor alpha1/alpha2 Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 253228 |
| 规格： | 0.1 ml |
| 产品描述： | Thyroid hormones are essential for development of the central nervous system. Deficits in these hormones during development affect cognitive functions as learning and memory. Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRa1, TRa2, TRb1 and TRb2. TRa1, TRb1 and TRb2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | Mouse IgG1 |
| 免疫原： | KLH-conjugated peptide encompassing a sequence within the N-term region of human thyroid hormone receptor, a1/a2-isotype. |
| 适用物种： | H, M, R, D |
| 应用范围： | E, WB |
| 应用说明： | E: 1:500-1:1,000; WB: 1:1,000 |
| 别名： | Nuclear receptor subfamily 1 group A member 1; V-erbA-related protein 7; EAR-7; c-erbA-1; c-erbA-alpha |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
