| 产品名称： | Nucleophosmin (7H10) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 252594 |
| 规格： | 0.1 ml |
| 产品描述： | Nucleophosmin (NPM) is a major nucleolar protein which is 20 times more abundant in tumor or proliferating cells than in normal resting cells. NPM has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication and molecular chaperoning activities . The NPM is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | Mouse IgG1 |
| 免疫原： | Purified recombinant fragment of human NPM expressed in E. coli. |
| 适用物种： | H, Mk |
| 应用范围： | WB, IHC, IF |
| 应用说明： | WB: 1:500-1:2000; IHC: 1:200-1:1000; IF: 1:200-1:1000 |
| 别名： | Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Numatrin; Nucleolar protein NO38; NPM1; NPM |
| 形态： | Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件： | Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 参考文献： |
