| 产品名称： | Tyrosine Hydroxylase (Ser40) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 252593 |
| 规格： | 0.1 ml |
| 产品描述： | Tyrosine hydroxylase (TH) catalyzes the conversion of tyrosine to L-DOPA, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. Nerve cells with TH content are referred to as catecholaminergic cells and occurs mainly in the brain and adrenal glands. Defects in TH are the cause of Segawa syndrome, translating in progressive difficulty in walking. The activity of TH is also regulated by phosphorylation. Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs. |
| 克隆类型： | Rabbit Polyclonal Antibody, Phosphospecific Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser40 of rat tyrosine hydroxylase. |
| 适用物种： | R |
| 应用范围： | E, WB, IF, IHC |
| 应用说明： | E: 1:1,000; WB: 1:1,000; IF: 1:1,000; IHC: 1:1,000 |
| 别名： | Tyrosine 3-hydroxylase; Tyrosine 3-monooxygenase; TH; TYH |
| 形态： | Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
