| 产品名称： | Synapsin I (Ser603) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 252583 |
| 规格： | 0.1 ml |
| 产品描述： | Synapsin I plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation. Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Serine 603 is the site on synapsin I that is phosphorylated by calcium calmodulin kinase II and by p21-activated kinases. Phosphorylation of this site is thought to regulate synaptic vesicle function. |
| 克隆类型： | Rabbit Polyclonal Antibody, Phosphospecific Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser603 of rat synapsin I. |
| 适用物种： | H, X, B, M, Zf, R |
| 应用范围： | E, WB |
| 应用说明： | E: 1:1,000; WB: 1:1,000 |
| 别名： | Synapsin-1; Synapsin I; SYN4 |
| 形态： | Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
