| 产品名称： | CREB (Ser133) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 252530 |
| 规格： | 0.1 ml |
| 产品描述： | As a dimer, CREB-1 (cAMP-responsive element-binding protein 1) binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters, to stimulate transcription. CREB-1 is activated by phosphorylayion on Ser-133 and Ser-142. Transcriptional activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. CREB-1 has been implicated in synchronization of circadian rhythmicity. It interacts with various proteins including TORC/CRTC, CREBBP, ARRB1. |
| 克隆类型： | Rabbit Polyclonal Antibody, Phosphospecific Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser133 of rat CREB. |
| 适用物种： | B, D, Ck, H, M, R, Sh, X, Zf |
| 应用范围： | E, WB |
| 应用说明： | E: 1:1,000; WB: 1:1,000 |
| 别名： | Cyclic AMP-responsive element-binding protein 1; cAMP response element-binding protein; CREB; CREB1; CREB-1 |
| 形态： | Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
