产品名称: | STAT3 Antibody |
说明书: | 【点击查看详细说明及参考图片】 |
货号: | 251107 |
规格: | 0.1 mg |
产品描述: | STAT3 (Signal transducer and activator of transduction 3) is a transcription factor that binds to the interleukin-6 responsive elements located in the promoter regions of various acute-phase protein genes. STAT3 is activated by IL-31 receptor pathway. Active STAT3 consists in homodimers or heterodimers with family member STAT1 and serine phosphorylation is important for DNA-binding and transcriptional activities. Defects in STAT3 are the cause of hyperimmunoglobulin E recurrent infection syndrome (Job syndrome). |
克隆类型: | Rabbit Polyclonal Antibody |
亚型: | Rabbit Ig |
免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human STAT3. |
适用物种: | H, M, R, P |
应用范围: | E, WB, IHC |
应用说明: | E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:100-1:500 |
别名: | Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF |
形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
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