Paxillin Antibody_Paxillin抗体

Paxillin Antibody产品详细介绍：

产品名称：	Paxillin Antibody
说明书：	【点击查看详细说明及参考图片】
货号：	251787
规格：	0.1 mg
产品描述：	Paxillin is a signal transduction adaptor protein. The C-terminal region of paxillin contains four LIM domains which target paxillin to focal adhesions, presumably through a direct association with the cytoplasmic tail of beta-integrin. The N-terminal region of paxillin is rich in protein–protein interaction sites. The proteins that bind to paxillin are diverse and include protein tyrosine kinases, such as Src and FAK, structural proteins, such as vinculin and actopaxin, and regulators of actin organization, such as COOL/PIX and PKL/GIT. Paxillin is tyrosine-phosphorylated by FAK and Src upon integrin engagement or growth factor stimulation, creating binding sites for the adapter protein Crk.
克隆类型：	Mouse Monoclonal Antibody
亚型：	Mouse IgG1
免疫原：	Recombinant C-terminal chicken paxillin (aa 305-559)
适用物种：	H, M, R, Ck
应用范围：	E, WB, ICC
应用说明：	E: 1:500-1:1,000; WB: 1:100-1:500; ICC: 1:100-1:500
别名：	Paxillin; PXN
形态：	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
保存条件：	Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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