| 产品名称： | Androgen receptor Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 252078 |
| 规格： | 0.1 mg |
| 产品描述： | Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3. The androgen receptor binds DNA as a homodimer. The androgen receptor is part of a ternary complex containing AR, EFCAB6/DJBP and PARK7. The androgen receptor interacts with HIPK3 and NR0B2 in the presence of androgen. The ligand binding domain interacts with MYST2/HBO1 in the presence of dihydrotestosterone. Defects in the androgen receptor are the cause of spinal and bulbar muscular atrophy X-linked type 1 (SMAX1), also known as Kennedy disease. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human androgen receptor. |
| 适用物种： | H, M, R |
| 应用范围： | E, WB |
| 应用说明： | E: 1:10,000-1:50,000; WB: 1:200-1:1,000 |
| 别名： | Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR; DHTR; NR3C4 |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
