
Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.
Product Name:IDE/Insulin Degrading Enzyme Mouse Monoclonal Antibody
Clone Number: 4H5
Isotype: IgG1
Storage Buffer :PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol
Storage instructions:-20°C. Do not aliquot the antibody
Recommended dilutions: WB: 1:1,000 IHC: 1:200
Optimal dilutions should be determined by the end user.
Specificity: IDE Mouse Monoclonal antibody detects endogenous IDE proteins.
Molecular Weight: 118KD
Form: Liquid
Reactivity:H

Western blot analysis of 1) Hela, 2) HepG2,with IDE Mouse mAb diluted at 1:2,000.

Western blot analysis of Hela, HepG2,with IDE Mouse mAb diluted at 1:2,000.