Rp-8-Br-cGMPS

Rp-8-Br-cGMPS
Cell-permeable, phosphodiesterase-resistant cGMP antagonist. Reversed NO stimulation of random migration in rabbit neutrophils. Used at 30µM to cometively inhibit 8-Br-cGMP relaxation of rabbit aortas. The product is not sterile. Resistant to nucleotide-dependent phosphodiesterases; no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to cyclic GMP or Rp-cGMPS.
Product Specification

Formula: C10H10BrN5O6PS . Na
 
MW: 462.2
 
CAS: 150418-07-8
 
Purity: ≥98% (HPLC)
 
Appearance: White lyophilized powder.
 
Solubility: Soluble in water (25mg/ml).
 
Shipping: Ambient
 
Long Term Storage: -20°C
 
Use/Stability: Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.

Rp-8-Br-cGMPS


Rp-8-Br-cGMPS



Rp-8-Br-cGMPS