CST SignalSilence® siRNA试剂 SignalSilence® Control siRNA (Unconjugated)

Cell Signaling Technology (CST)的SignalSilence^® siRNA试剂允许研究者YZ特定蛋白的表达。这种产品利用的是RNA干扰的方法，所谓RNA干扰是指通过双链RNA分子进入细胞可以选择性地沉默相应基因的表达。针对每个蛋白，我们提供两个一样有效的siRNA（siRNA I 和 II）。另外，荧光标记的非目标fluorescein-labeled non-targeted siRNA control #6201 可用作对照监控转染效率，而非偶联的对照unconjugated control siRNA #6568 可以用来控制特异性。现在有针对人和小鼠目标蛋白的SignalSilence^® siRNA

RNA interference is a method whereby gene expression can be selectively silenced through the delivery of double stranded RNA molecules into the cell. The introduction of a specific small interfering RNA (siRNA) strand prevents the translation of a target protein message through RNA degradation. SignalSilence® Control siRNA (Unconjugated) is a siRNA sequence that will not lead to the specific degradation of any cellular message. It is intended to serve as a negative control for experiments using targeted siRNA transfection. This duplex contains the same scrambled sequence used in SignalSilence® Control siRNA (Fluorescein Conjugate) #6201.

RNA干扰技术是一种通过向细胞中输入双链RNA分子，选择性沉默基因表达的方法。一种特定的小干扰RNA的引入可以通过降解RNA来阻止目的蛋白的翻译。SignalSilence ® Control siRNA （未标记）是一种小干扰RNA（siRNA），不能导致细胞信号的特定降解，而用来作为靶siRNA转染的阴性对照。这种双链RNA与SignalSilence ® Control siRNA (Fluorescein Conjugate) #6201具有相同的密码序列。