Peprotech因子Recombinant Human IL-11新品促销
产品编号:
200-11
别名:
AGIF (Adipogenesis inhibitory factor)
描述:
IL-11 is a multifunctional cytokine produced by stromal cells, such as fibroblasts, epithelial cells ａnd osteoclasts. It is expressed in a wide variety of tissues, including thymus, lung, bone, connective tissue ａnd central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid ａnd megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines, ａnd protects against gastromucosal injury. Recombinant Human IL-11 is a 19.3 kDa protein consisting of 179 amino acid residues.
氨基酸序列:
MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine T11 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
交叉反应:
Monkey, Mouse, Human
研究领域:
 | 血管生成/ 心血管 |  | 细胞凋亡 |
 | 癌症 |  | 免疫系统 |
 | 炎症 |  | 干细胞及分化 |
原产国:
USA
