Recombinant Murine FGF-basic优势产品产品编号:
450-33
别名:
Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
描述:
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth ａnd regeneration of a variety of tissues, by promoting cellular proliferation ａnd differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells ａnd endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c ａnd 4. Recombinant Murine FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues.
氨基酸序列:
PALPEDGGAA FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHV KLQLQAEERG VVSIKGVCAN RYLAMKEDGR LLASKCVTEE CFFFERLESN NYNTYRSRKY SSWYVALKRT GQYKLGSKTG PGQKAILFLP MSAKS
来源:
E.coli
纯度:
Greater than 95% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.1 ng/ml corresponding to a specific activity of ≥ 1 x 107units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
交叉反应:
Rabbit, Mouse, Rat, Human
研究领域:
 | 血管生成/ 心血管 |  | 癌症 |
 | 细胞培养 |  | FGF超家族 |
 | 炎症 |  | 神经生物学 |
 | 增殖 |  | 干细胞及分化 |
 | 创伤修复 | |
原产国:
USA
