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Recombinant Human FGF-acidic Peprotech细胞因子厂家

产品信息
生长因子此类产品包括人、小鼠或大鼠的细胞外蛋白,多数情况下可启始或影响通过细胞表面受体传递的信号。下列产品包括人、小鼠和大鼠的白细胞介素、集落刺激因子、生长因子、干扰素、脂肪因子、BMP蛋白、FGFs、TNFs、可溶性受体、细胞外结合蛋白、非抑制型丝氨酸蛋白酶抑制剂及其他免疫调节蛋白等。
Recombinant Human FGF-acidic Peprotech细胞因子厂家

产品编号:
100-17A
别名:
Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta
描述:
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant Human FGF-acidic is a 16.8 kDa protein consisting of 141 amino acid residues.
氨基酸序列:
MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
来源:
E.coli
纯度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
生物活性:
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105units/mg. 

Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.5 ng/ml in the presence of 10 μg/ml heparin, corresponding to a specific activity of ≥ 2 x 106units/mg.
 
 
 
 
交叉反应:
Cow, Mouse, Pig, Rat, Shark, Squid, Human, Hamster, Hagfish, Leech, N/A
研究领域:
血管生成/ 心血管 癌症
细胞培养 FGF超家族
神经生物学 增殖
干细胞及分化 创伤修复
 
 
原产国:
USA
仅用于研究。不适用于诊断或ZL。

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