Tocris原装 ZD 7288价格, Tocris 1000/10说明书
- 型号：10MG/50MG
- 产地：中国大陆
- 供应商：杰辉生物（北京）科技发展有限公司
- 供应商报价：1
- 标签：Tocris原装 ZD 7288价格, Tocris 1000/10说明书,生物试剂,生化试剂,供应Tocris原装 ZD 7288价格, Tocris 1000/10说明书,杰辉生物（北京）科技发展有限公司
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Tocris原装 ZD 7288价格, Tocris 1000/10说明书
D 7288Cat. No. 1000
| Tocris | 1000/10 | ZD 7288 （10 MG） | 10 MG |
| Tocris | 1000/50 | ZD 7288 （50 MG） | 50 MG |
Alternative Name: ICI D7288
Chemical Name: 4-Ethylphenylamino-1,2-dimethyl-6-m
Biological ActivitySino-atrial node function modulator; blocks the hyperpolarization activated cation current If （HCN channel）. Blocks Ih in central neurons. Increases NMDA-evoked noradrenalin release in rat brain in vitro.
echnical DataM.Wt:
BoSmith et al （1993） Inhibitory actions of ZENECA ZD7288 on whole cell hyperpolarization activated inward current （If） in guinea-pig dissociated sinoatrial node cells. Br.J.Pharmacol. 110 343. PMID:7693281.
Harris ａnd Constanti （1995） Mechanism of block by ZD7288 of the hyperpolarization-activated inward rectifying current in guinea-pig substantia nigra neurons in vitro. J.Neurophysiol. 74 2366. PMID:8747199.
Green et al （1996） Pharmacological characterization of the inwardly rectifying current in the smooth muscle cells of the rat bladder. Br.J.Pharmacol. 119 1509. PMID: 8982495.
Klar et al （2003） Ih channels as modulators of presynaptic terminal function: ZD7288 increases NMDA-evoked [3H]-noradrenaline release in rat neocortex slices. Naunyn Schmiedebergs Arch.Pharmacol. 367 422. PMID: 12690435.
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The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
