EGFR (C-term),Rabbit Monoclonal IgG
- 产地:中国大陆
- 供应商:上海谱振生物有限公司
- 供应商报价:电议
- 标签:EGFR (C-term),Rabbit Monoclonal IgG,智能控制,人机界面,供应EGFR (C-term),Rabbit Monoclonal IgG,上海紫一试剂厂
EGFR (C-term) Rabbit Monoclonal IgG |
Cas 号: |
分子式: |
别 名: | Recept o r tyrosine-protein kinase ErbB-1 |
订货信息: |
货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 订购 |
EGFR (C-term) | 100ul | 询价 | 现货 | 订购 |
性 状: | 【反应特异性】Human 【克隆 ID】E235 |
质量标准: | 【产品介绍】Epidermal growth fact o r recept o r (EGFR) is a 170 kDa transmembrane glycoprotein recept o r tyrosine kinase that, activated by epidermal growth fact o r (EGF), affects cell growth a n d differentiation (1). Binding of EGF o r TGF alpha to EGFR activates tyrosine kinase activity of the recept o r (2). The carboxy terminal tyrosine residues on EGFR, Tyr 1068, Tyr 1148, a n d Tyr 1173, are the maj o r sites of autophosph o r ylation, which occurs as a result of EGF binding (3). Once activated, EGFR phosphotyrosines Y-1068 a n d Y-1173 mediate the binding of Grb2 to the EGFR. Another autophosph o r ylation site, Tyr 1086, is situated within the cytoplasmic domain, a n d is phosph o r ylated to a higher extent by c-Src than by EGFR (4).
EGFR (C-term),Rabbit Monoclonal IgG EGFR (C-term),Rabbit Monoclonal IgG B. Immunoflu o r escent staining of A431 cells |