DLC8 (N-term),Rabbit Monoclonal IgG
- 产地:中国大陆
- 供应商:上海谱振生物有限公司
- 供应商报价:电议
- 标签:DLC8 (N-term),Rabbit Monoclonal IgG,智能控制,人机界面,供应DLC8 (N-term),Rabbit Monoclonal IgG,上海紫一试剂厂
DLC8 (N-term) Rabbit Monoclonal IgG |
Cas 号: |
分子式: |
别 名: | Dynein light chain LC8-type 1, 8 kDa dynein light chain, DLC8, Protein inhibit o r of neuronal nitric oxide synthase, PIN |
订货信息: |
货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 订购 |
DLC8 (N-term) | 100ul | 询价 | 现货 | 订购 |
性 状: | 【反应特异性】Human , Mouse , Rat 【克隆 ID】EP1660Y |
质量标准: | 【产品介绍】DLC8 protein bound efficiently to gephyrin in in vitro binding assays a n d colocalized with gephyrin during coexpression in HEK293 cells. The binding site f o r DLC8 was mapped to a fragment of 63 amino acids within the central linker domain of gephyrin. In hippocampal neurons, endogenous DLC8 protein was enriched at synaptic sites identified by synaptophysin a n d gephyrin immunostaining. Because DLC8 has been described as stoichiometric components of cytoplasmic dynein a n d myosin-Va complexes, results suggest that mot o r proteins are involved in the subcellular localization of gephyrin (1). DLC8 was identified as a transp o r t molecule in the cytoplasm. DLC8 co-localizes with TRPS1 in dot-like structures in the cell nucleus. In an electroph o r etic mobility shift assay it was shown that the interaction of DLC8 a n d TRPS1 lowers the binding of TRPS1 to the GATA consensus sequence. In addition DLC8 is able to suppress the transcriptional repression activity of TRPS1 (2).
DLC8 (N-term),Rabbit Monoclonal IgG A. Western blot analysis on HeLa cell lysate using DLC8 (N-term),Rabbit Monoclonal IgG B. Immunohistochemical staining of paraffin-embedded |