Cytokeratin 8，Rabbit Monoclonal IgG
- 产地：中国大陆
- 供应商：上海谱振生物有限公司
- 供应商报价：电议
- 标签：Cytokeratin 8，Rabbit Monoclonal IgG,智能控制,人机界面,供应Cytokeratin 8，Rabbit Monoclonal IgG,上海紫一试剂厂
产品库
| Cytokeratin 8 Rabbit Monoclonal IgG |
| Cas 号： |
| 分子式： |
| 别 名： | Cytokeratin-8, CK-8, Keratin-8, K8 |
| 订货信息： |
| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 订购 |
| Cytokeratin 8 | 100ul | 询价 | 现货 | 订购 |
| 性 状： | 【反应特异性】Human 【用途】WB , IHC , ICC , FC , IP |
| 质量标准： | 【产品介绍】Keratins, the intermediate filament proteins of epithelial cells, connect to desmosomes, the cell-cell adhesion structures at the surface membrane. Among the various intermediate filament （IF） proteins, cytokeratin 8 （CK8） is especially remarkable as it is produced early in embryogenesis, is the only type-II CK occurring in many simple epithelial cells, a n d can also be synthesized in certain non-epithelial cells （1）. Keratin 8 a n d 18 （CK8/18） are the maj o r keratin pair in simple-type epithelia, as found in the liver, pancreas, a n d intestine （2）. While K8/K18 are essential f o r maintaining structural integrity, there is accumulating evidence indicating that they also exert non-mechanical functions. It has been rep o r ted that K8/K18-free hepatocytes from K8-null mice are m o r e sensitive to Fas-mediated apoptosis, in line with an increased Fas density at the cell surface a n d an altered c-Flip regulation of the anti-apoptotic ERK1/2 signaling pathway （3）.
Cytokeratin 8，Rabbit Monoclonal IgG Cytokeratin 8，Rabbit Monoclonal IgG A. Western blot analysis on A431 cell lysate using B. Immunohistochemical analysis of paraffin-embedded |
