Anti-factor VIII(FVIII) human第八因子相关抗原抗体

本公司经销factor VIII（FVIII） human，第八因子相关抗原抗体，克隆类型为polyclonal，宿主来源是Rabbit，factor VIII（FVIII） human第八因子相关抗原抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-0332R
英文名称：Anti-factor VIII（FVIII） human
中文名称：第八因子相关抗原抗体
其他名称：名coagulation factor VIII; Ahf; Antihemophilic factor; Coagulation factor VIII; Coagulation factor VIII associated protein b; Coagulation factor VIII isoform b; Coagulation factor VIII procoagulent component; Coagulation factor VIIIc; Dna segment on chromosome x unique 1253 expressed sequence; Dxs1253e; F8; F8 protein; F8b; F8c; Factor VIII F8b; FactorVIII; FVIII; Hema; Hema coagulation factor VIIIc procoagulent component; Hemophilia a; Hemophilia classic; OTTHUMP00000061446; Procoagulant component.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 230kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：Factor VIII, along with calcium ａnd phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa. Interacts with VWF. VWF binding is essential for the stabilization of F8 in circulation. Secreted protein; extracellular space. Domain F5/8 type C 2 is responsible for phospholipid-binding ａnd essential for factor VIII activity. Defects in F8 are the cause of hemophilia A （HEMA）. Belongs to the multicopper oxidase family. Factor VIII-related Antigen （又称：凝结因子VIII,抗血友病因子）第VIII因子抗体用于血管源性良性和恶性肿瘤的诊断，也用于遗传性血友病的研究。在正常动脉、静脉、毛细血管及心脏内细胞的血管内皮细胞上阳性表达。在巨核细胞及血小板上也有表达。 第八因子相关抗原-Ⅷ因子抗体:是一种糖蛋白，广泛存在于血管上皮、肝脏、脾窦上皮、及淋巴内皮细胞，是血管内皮细胞及其内源性良恶性肿瘤的特异性标记。主要用于血管原性良恶性肿瘤和血管肉瘤的诊断。少数副睾、子宫和输卵管的腺癌样瘤也有表达.产品图片Tissue/cell: human colon carcinoma; 4% Paraformaldehyde-fixed ａnd paraffin-embedded; Antigen retrieval: citrate buffer （ 0.01M, pH 6.0 ）, Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer （normal goat serum,C-0005） at 37℃ for 20 min; Incubation: Anti-factor VIII（FVIII）（human） Polyclonal Antibody, Unconjugated（bs-0332R） 1:200, overnight at 4°C, followed by conjugation to the secondary antibody（SP-0023） ａnd DAB（C-0010） stainingAntigen: bs-0332P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG（bs-0295G-HRP） at 1: 5000; TMB（C-0024） staining; Read the data in MicroplateReader by 450nm.