酪蛋白激酶2相互作用蛋白1抗体,Anti-CKIP-1抗体

博研生物抗体售前、售中、售后免费技术服务，欢迎致电索说明书

客服电话：021 60340850    021 60340830    021 60340820
客服QQ ：827774711    349199432     372584443 
产品名称  酪蛋白激酶2相互作用蛋白1抗体,Anti-CKIP-1抗体                                             
产品编号 BYk-1330R     

相关标记 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-Cy5 PE-Cy5.5
PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
浓 度 1mg/1ml
抗体来源 Rabbit OR MOUSE
克隆类型 polyclonal or monoclonal
产品类型 一抗
产品用途  科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
性 状 Lyophilized or Liquid
亚 型 IgG     

酪蛋白激酶2相互作用蛋白1抗体,Anti-CKIP-1抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

酪蛋白激酶2相互作用蛋白1抗体,Anti-CKIP-1抗体产品说明：

Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein （CP）. May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2（CK2）. Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity （plasma membrane bound AP-1 regulator that translocates to the nucleus） ａnd the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation. [SUBUNIT] Heterodimer or homodimer. [SUBCELLULAR LOCATION] Cell membrane. Nucleus. Cytoplasm. [TISSUE SPECIFICITY] Abundantly expressed in skeletal muscle ａnd heart, moderately in kidney, liver, brain ａnd placenta ａnd sparingly in the pancreas ａnd lung. Easily detectable in cancer cell lines such as MOLT-4, HEK293 ａnd Jurkat cells.