GDF15/MIC-1生长分化因子15/巨嗜细胞YZ因子1抗体

本公司经销GDF15/MIC-1，生长分化因子15/巨嗜细胞YZ因子1抗体，克隆类型为polyclonal，宿主来源是Rabbit，GDF15/MIC-1生长分化因子15/巨嗜细胞YZ因子1抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-3818R
英文名称：Anti-GDF15/MIC-1
中文名称：生长分化因子15/巨嗜细胞YZ因子1抗体
其他名称：名GDF 15; GDF-15 Growth differentiation factor 15; Growth/differentiation factor 15; Macrophage inhibitory cytokine 1; MIC 1; MIC-1; MIC1; NAG 1; NAG1; NRG 1; NRG1; NSAID （nonsteroidal anti inflammatory drug） activated protein 1; NSAID; NSAID regulated protein 1; PDF; PLAB; Placental bone morphogenetic protein; Placental bone morphogenic protein; Placental TGF beta; placental transformation growth factor beta; Prostate differentiation factor; PTGF beta; PTGFB; prostate derived factor.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 12.5/34kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Growth differentiation factor 15 （GDF15） is a member of the bone morphogenetic protein （BMP） family ａnd the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative ａnd pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth ａnd differentiation in both embryonic ａnd adult tissues.GDF15 is an important downstream mediator of DNA damage signaling ａnd a transcriptional target of p53. Subcellular Location : Secreted.Tissue Specificity : Highly expressed in placenta, with lower levels in prostate ａnd colon ａnd some expression in kidney.Similarity : Belongs to the TGF-beta family.生长分化因子15（GDF15）是骨形态发生蛋白（BMP）和转化生长因子-β超家族成员。GDF-15又叫巨噬细胞YZ因子（macrophage inhibiting cytokine，MIC）-1、胎盘转化生长因子 （placental transformation growth factor，PTGF）-β、前列腺衍生因子（prostate derived factor，PDF）和胎盘骨形态发生蛋白（placental bone morphogeneticprotein，PLAB）。有学者认为：GDF-15在肿瘤发展的不同阶段发挥着不同的生物学作用；随着肿瘤的发SF展，GDF-15可能表达不同形式的蛋白，在肿瘤发生的早期阶段可能发挥抑瘤作用，而在肿瘤发展的后期阶段发挥促瘤作用。