本公司经销SR1/Sorcin，抗药蛋白抗体，克隆类型为polyclonal，宿主来源是Rabbit，SR1/Sorcin抗药蛋白抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！
货号：BY-9871R
英文名称：Anti-SR1/Sorcin
中文名称：抗药蛋白抗体
其他名称：名22 kDa protein;Calcium binding protein amplified in mutlidrug resistant cells;CP 22;CP-22;CP22;SCN;Sorcin （class 4 gene）;Sorcin;SORCN_HUMAN;SRI;V19.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 22kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Sorcin is a highly conserved protein, with 95% homology between hamster ａnd human sorcin sequences. Sorcin has four putative Ca-binding domains, two of which exhibit strong homology to calmodulin “EF hand” motifs. Calcium binding directly to sorcin has been demonstrated by in vitro assays. Sorcin is closely related to members of calpain ａnd sarcoplasmic Ca2+-binding protein subfamilies. Sorcin undergoes calcium-dependent translocation from the cytosol to cellular membranes. Sorcin binds to ａnd modulates ryanodine receptors ａnd is widely distributed including heart ａnd brain tissues. At the subcellular level, sorcin localizes to T-tubule junctions of cardiac sarcoplasmic reticulum.Subcellular Location : Cytoplasm. Sarcoplasmic reticulum membrane. Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels.Tissue Specificity : Detected in cardiac myocytes.
