本公司经销RGS4,精神分裂症相关蛋白9抗体,克隆类型为polyclonal,宿主来源是Rabbit,RGS4精神分裂症相关蛋白9抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
货号:BY-9452R
英文名称:Anti-RGS4
中文名称:精神分裂症相关蛋白9抗体
其他名称:名Regulator of G protein signalling 4;Regulator of G-protein signaling 4;RGP 4;RGP-4;RGS 4;RGS4;RGS4_HUMAN;Schizophrenia disorder 9;SCZD 9;SCZD9;MGC2124;MGC60244.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 28, 40kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.Involvement in disease;Genetic variation in RGS4 is associated with susceptibility to schizophrenia type 9 (SCZD9) . A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder.