本公司经销PP1C gamma，蛋白磷酸酶γ1抗体，克隆类型为polyclonal，宿主来源是Rabbit，PP1C gamma蛋白磷酸酶γ1抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！
货号：BY-5422R
英文名称：Anti-PP1C gamma
中文名称：蛋白磷酸酶γ1抗体
其他名称：名PP 1G; PP1G; PP-1G; PPP-1G; PPP 1G; PPP1CC; PPP1G; PP1C gamma; Protein phosphatase 1C catalytic subunit; Serine/threonine phosphatase 1 gamma; Serine/threonine protein phosphatase PP1 gamma catalytic subunit; Protein phosphatase 1 gamma 2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 35kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, chk, hrs, cow, dog
产品介绍：Protein phosphatase 1 （PP1） is essential for cell division, ａnd participates in the regulation of glycogen metabolism, muscle contractility ａnd protein synthesis. The protein is involved in regulation of ionic conductances ａnd long term synaptic plasticity. It may play an important role in dephosphorylating substrates such as the postsynaptic density associated Ca （2+）/calmodulin dependent protein kinase II.PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC （PP1C gamma）, which is folded into its native form by inhibitor 2 ａnd glycogen synthetase kinase 3, ａnd then complexed to one or several targeting or regulatory subunits. PPP1R12A ａnd PPP1R12B mediate binding to myosin. PPP1R3A, PPP1R3B, PPP1R3C ａnd PPP1R3D mediate binding to glycogen.Subunit : PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC, which is folded into its native form by inhibitor 2 ａnd glycogen synthetase kinase 3, ａnd then complexed to one or several targeting or regulatory subunits. PPP1R12A, PPP1R12B ａnd PPP1R12C mediate binding to myosin. PPP1R3A （in skeletal muscle）, PPP1R3B （in liver）, PPP1R3C, PPP1R3D ａnd PPP1R3F （in brain） mediate binding to glycogen. Interacts with cyanobacterial toxin microcystin; disulfide-linked. Interacts with PPP1R3B ａnd PPP1R7. Isoform gamma-2 interacts with SPZ1 （By similarity）. Component of the MLL5-L complex, at least composed of MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB ａnd OGT. Interacts with CDCA2. PPP1R1 ａnd PPP1R15B mediate binding to EIF2S1. Part of a complex containing PPP1R15B, PP1 ａnd NCK1/2. Interacts with IKFZ1; the interaction targets PPP1CC to pericentromeric heterochromatin, dephosphorylates IKAROS, stabilizes it ａnd prevents it from degradation. Interacts with PPP1R42; the interaction is direct （By similarity）. Interacts with NOM1 ａnd PPP1R8. Component of the PTW/PP1 phosphatase complex, composed of PPP1R10/PNUTS, TOX4, WDR82, ａnd PPP1CA or PPP1CB or PPP1CC. Interacts with PPP1R8. InteractsSubcellular Location : Cytoplasm. Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus speckle. Chromosome, centromere, kinetochore. Cleavage furrow. Midbody. Mitochondrion.Similarity : Belongs to the PPP phosphatase family. PP-1 subfamily.
