本公司经销PKA gamma，蛋白激酶Aγ抗体，克隆类型为polyclonal，宿主来源是Rabbit，PKA gamma蛋白激酶Aγ抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！
货号：BY-3964R
英文名称：Anti-PKA gamma
中文名称：蛋白激酶Aγ抗体
其他名称：名KAPG; PKA C gamma; PRKACG; Protein kinase cAMP dependent catalytic gamma; Serine （threonine） protein kinase.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 40kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：PKA （or cAPK） is a cyclic AMP dependent protein kinase. When activated by the second messenger cAMP, PKA mediates diverse cellular mechanisms, including proliferation, ion transport, regulation of metabolism, plus gene transcription. PKA is comprised of two dimers of two subunits, R （regulatory） ａnd C （catalytic）. Two families of R subunit （RI ａnd RII） ａnd three C subunit isoforms （C alpha, C beta, ａnd C gamma） have been identified each possessing distinct cAMP binding properties ａnd resulting in different phosphorylation states. C subunit is activated through autophosphorylation ａnd direct phosphorylation at Thr197 by PDK-1. Tissue specific expression of C gamma, indicates pressure on C gamma during evolution, acting to modulate it in a functionally specific way. Certain amino acid substitutions make C gamma a distinct member of the cAMP dependent subfamily of protein kinases, ａnd suggest that C gamma may be distinct in its protein substrate specificity or its interaction with the different regulatory subunits.
